The BioSil Clinical Trials

Proven Results, Statistically Significant

Clinical Trial Protocol
Researchers used the gold standard of clinical trial protocols, randomized, double-blind, placebo-controlled, parallel group. This is the same protocol that the US government requires the pharmaceutical companies to use. It ensures accuracy and repeatable results.

Who Participated

For skin and nails, participants were all healthy women in their 40’s, 50’s and 60’s who showed clear signs of sun-damaged skin on top of natural-aged skin. That meant skin wrinkles, sagging skin, and loss of skin elasticity caused by decreased collagen, a degraded collagen “mesh” and degraded elastin. These women were chosen because over time the changes caused by the sun would occur naturally. For hair, the participants were all women between the ages of 18 and 65 who all showed signs of weak, thinning, dull hair. The large cross section of ages eliminated the possibility of strictly age-related thinning.


All results in the BioSil clinical trials are considered statistically significant (p<.05). “Statistical significance” means that the results obtained have come from the compound tested (in this case BioSil’s patented ch-OSA®). This reduces any possibility of “chance” to a great extent. BioSil is clinically proven to:

- Reduce fine line and wrinkles by 30.0%*
- Increase skin elasticity 89.0%*
- Strengthen hair by 13.1%§
- Thicken hair by 12.8%§
- Dramatically strengthen nails (see VAS Scores in “Clinical Trials”)*

* After 20 weeks versus the placebo group.
§ After 36 weeks versus the placebo group.

PLEASE NOTE: All BioSil results are clinically proven. Often times, you see products making the claim “clinically tested” or “clinically studied.” This says nothing about the results, which could have shown no improvement at all.

Clinical Studies: 

Barel et al 2005
Wickett et al 2007
Spector et al 2008